中西醫整合治療更有效
恭賀!
本院傳統醫學科戴承杰主任及血液腫瘤科戴承正主任論文「併用中藥對接受化療癌症病人肝臟保護及完成化療之成效 」，於2009年10月被美國實證醫學期刊接受
Mei-Ling Liu, Li-Yin Chien,Cheng-Jeng Tai, Kuan-Chia Lin,
Chen-Jei Tai*. Effectiveness of Traditional Chinese Medicine for Liver
Protection and Chemotherapy Completion among Cancer Patients, (2009.10) eCAM - ECAM-09-0193.R2 (Accepted)
*通訊作者
Abstract
Purpose:
While traditional Chinese medicine (TCM) is
widely used among
Chinese patients with cancer, studies evaluating the effectiveness of TCM using
objective indicators are rare. We examined the effectiveness of TCM for liver
protection and completion of chemotherapy among patients with cancer receiving
chemotherapy.
Patients and methods:
We used a case-control design to examine
the medical records of patients with cancer who received chemotherapy in a
teaching hospital in
Results:
Patients who had concomitant TCM with
chemotherapy had lower serum ALT and AST during chemotherapy than the controls
given that the age, sex, cancer stage, radiotherapy sites, cancer diagnosis,
and potential hepatotoxicity of the chemotherapeutic
drugs were controlled for in the model (β = -3.48, 95% CI: -10.08 – 3.11 for AST; β = -5.95, 95% CI: -11.47 – -0.44 for ALT). There was no significant difference
between the case and control groups for odds of completing one course of
chemotherapy.
Conclusion:
Use of TCM with chemotherapy resulted in protection of the liver during chemotherapy, as manifested by lower serum AST and ALT levels.
Key words: traditional Chinese medicine, liver function, chemotherapy
結論：中藥能有效保護因化療期間導致之肝功能異常